Listed below are the cancers in which peritoneal spread is treatable
Colon Cancer: In colon cancer (cancer of the large bowel), peritoneal cancer will develop in about 15% of the patients. Patients with peritoneal implants often have seeding in the liver or lungs. In 3% of all patients however, seeding is limited to the peritoneum. It is for this subgroup of patients cytoreductive surgery and HIPEC may be an option. In some selected patients with 1-3 tumors in the liver and peritoneal cancer, surgery could still be possible. Read more..
Ovarian Cancer : In ovarian cancer (cancer of the ovaries), peritoneal cancer will develop in about 75% of the patients. In patients whom the seeding is limited to the peritoneum , cytoreductive surgery is the treatement . Worldwide, HIPEC is being increasingly used to treat patients with ovarian cancer especially with stage 3 and 4 and recurrent ovarian cancer. Read more..
Pseudomyxoma Peritonei: A pseudomyxoma is a rare form of peritoneal cancer. It originates from tumors that contain a jelly like substance, mucin (mucinous tumors) , the common ones being appendicular tumors, ovarian and colorectal tumors. in the abdominal cavity. These tumor cells continue to produce jelly, which results in a swollen abdomen and sticking together of parts of the small bowel leading to intestinal obstruction. Cytoreductive surgery and HIPEC is regarded as the first choice treatment of this slowly growing tumor. Read more…
Mesotheliomas : A mesothelioma is also a rare form of peritoneal cancer which begins in the cells of the peritoneum itself. In a first, more benign, type of mesothelioma, there is much ascites (peritoneal fluid) and only small tumor implants. In a second, more malignant, type of mesothelioma, there is little ascites but larger tumor implants. Cytoreductive surgery and HIPEC can be an option, especially for the first type. Read more…
Gastric Cancer: Peritoneal seedings are frequent in stomach cancer. Stomach cancer is however much more aggressive than the cancers described above and cytoreductive surgery and HIPEC may done for selected patients with low tumor volume and good general health.
Desmoplastic Small Round Cell Tumors(DSRCTs): This is a rare type of soft tissue sarcoma in the Ewings Sarcoma family of tumorsare. They are typically found in the abdomen and affect young males. Cytoreductive surgery and HIPEC has shown benefit in this cancer type. Read More..
Other Cancers: Peritoneal cancer can be caused by a lot of tumors inside or outside the abdominal cavity such as pancreas cancer, biliary cancer, sarcoma (cancer of the connective tissue) and breast cancer. At present, there are no scientific data to support the use of cytoreductive surgery and HIPEC in these settings. However, there could be some isolated cases in which circumstances favour this form of treatment and it might be used